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    Natural Mood & Mind Support

    A premium blend of saffron, curcumin, and zinc designed to help you stay steady, positive, and mentally clear.

Over 10,000,000 Happier Days!

“I honestly love this stuff. Taking this every day has
SIGNIFICANTLYimproved my overall well-being.”

Targeted Mood & Stress Support — Backed by Clinically Studied Botanicals

Support emotional balance and everyday resilience with a science-driven blend of affron® Saffron Extract, LONGVIDA® Curcumin, and high-absorption Zinc.

This advanced formula is designed to help:

  • Promote a positive mood and emotional well-being
  • Support the body’s stress response
  • Maintain brain and nervous system health

Each serving delivers precisely standardized extracts and essential nutrients—without unnecessary additives—so you can feel supported, focused, and balanced every day.

  • Corn Free

  • Dairy Free

  • Egg Free

  • Artificial Additive Free

  • Gluten & Yeast Free

    The BrainMD Promise

    OUR PRODUCTS ARE SUPERIOR IN FORMULA, INGREDIENTS, TASTE AND QUALITY.

    At BrainMD, we’ve dedicated our careers to helping people like you feel better with all natural, ethically sourced ingredients. Plus, they’re free of gluten, wheat, eggs, corn, sugars, artificial coloring or flavoring, and common toxins that many manufacturers don’t check for—like dioxins.

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      BRAIN HEALTH

      A 360 approach to optimal brain and physical wellness and purposeful living

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      SCIENCE & MEDICAL DATA

      Founded and formulated by the best doctors

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      PURITY OF INGREDIENTS

      Clinical-grade and free of toxins that others may not address

      Ingredients

      AFFRON® SAFFRON

      30 mg

      This is a highly concentrated and standardized nutraceutical extract of saffron, a spice that has been used in the Middle East for at least 2600 years. In clinical trials at a dose of 28 mg per day, this extract has performed extremely well for improving mood and anxiousness in both adults and adolescents.

      LONGVIDA® CURCUMIN

      400 mg

      The turmeric root parallels saffron as an Asian happiness herbal for at least 2600 years. This ingredient features excellent absorption of curcumin and has worked excellently in clinical trials at 400 mg per day or higher.

      Zinc

      20 mg

      This mineral is essential for the functioning of about 2000 different human proteins, of which at least 300 are enzymes. People with mood problems typically have low blood levels and supplementing with zinc often enhances mood.

      Make Your Brain (& Body) Happy

      The benefits of saffron are endless. Saffron has been used in Eastern medicine for thousands of years as a powerful antioxidant and aphrodisiac. Today, the “happiness spice” is recognized worldwide for its distinctive ability to improve mood and relieve feelings of anxiousness in both adults and adolescents.

      Because of its powerful aphrodisiac properties, saffron is used in many natural libido supplements.* But not all saffron supplements are created equal. Much of what’s sold today is loaded with other plants and artificial substances. That’s why we formulated our saffron supplement with the purest ingredients available.

      • Month 1

        Clinically studied nutrients get to work

      • Month 2-3

        Nutritional deficiencies are corrected (varies by person)

      • Month 4 & Beyond

        Amplify the benefits & support long-term health

        • OUR CEO SAYS •

        “This is my favorite product I take every day. The ingredients in Happy Saffron Plus are backed by 24 randomized control trials, but the reason I fell in love with this formula is that it supports mood, memory, and sexual function.”

        - Daniel G. Amen, MD 

        Award-Winning Saffron Extract

        affron® Saffron Extract is the most awarded and clinically backed saffron ingredient worldwide. It works fast – generally in 1 hour – to alleviate oxidative stress, balance neurotransmitters, facilitate neuroplasticity, and deliver hard-hitting brain and body benefits like better memory and improved sexual function.

        affron® is the best studied saffron for mood.* In a randomized, double-blind, placebo-controlled study, affron® intake of 28 mg/day for 4 weeks improved mood while helping to alleviate occasional stress, frustration, and tension by 41%, compared to placebo.

        Cutting-Edge Curcumin

        Longvida® curcumin is 95x more bioavailable than standard curcumin extracts and is the only curcumin extract in the world to use cutting-edge SLCP™ Technology to increase curcumin absorption.* Shown to be the most effective curcumin on the market, Longvida® is patented for cognition and anti-aging.* And, unlike many other forms of curcumin, it can effectively cross the blood-brain barrier.* 


        Clinical research shows that 400 mg of Longvida® supports cognition, memory, mood, and attention while reducing stress reactivity and fatigue.*6,7 Also, the same dosage supports a 16% increase in working memory within just 1 hour of taking the first dose!

        Get Happy (Without Side Effects!)

        Zinc is an essential micronutrient crucial to more than 300 enzymatic reactions. The body needs zinc to make energy, DNA and proteins, antioxidant enzymes, and to make new cells for immunity and healthy growth and development.

        Results from six randomized, double-blind, placebo-controlled studies suggest supplementing with zinc can improve mood in healthy individuals and people with mood problems.

        When combined with saffron and curcumin, this powerful trio of ingredients can help transform your mood and support your best health without any unwanted side effects.

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        Clinically Researched Benefits

        As a company firmly rooted in science, we use only clinically researched ingredients that create real results. Here are some of the benefits of taking the natural mood enhancer Happy Saffron Plus:

        Happier mood*

        Enhanced memory & cognition*

        Improved sexual function*

        Greater resilience to stress*

        Increased focus* 

        Decreased feelings of anxiousness*

        Better joint health & mobility*

        More energy*

        Appetite control*

        Founding Doctor

        DANIEL G. AMEN, MD 
        DOCTOR AND FOUNDER, BRAINMD Empty heading

        Dr. Daniel Amen’s mission is to end mental illness by creating a revolution in brain health. He is dedicated to providing the education, products, and services to accomplish this goal.

        Dr. Amen is a physician, adult and child psychiatrist, and founder of Amen Clinics with 11 locations across the U.S. Amen Clinics has the world’s largest database of brain scans for psychiatry totaling more than 210,000 SPECT scans on patients from 155 countries.

        He is the founder of BrainMD, a fast-growing, science-based nutraceutical company, and Amen University, which has trained thousands of medical and mental health professionals on the methods he has developed.

        Dr. Amen is one of the most visible and influential experts on brain health and mental health with millions of followers on social media. In 2020. Dr. Amen launched his digital series Scan My Brain featuring high-profile actors, musical artists, athletes, entrepreneurs, and influencers that airs on YouTube and Instagram. Over 90 episodes have aired, turning it into viral social media content with collectively millions of views.

        He has also produced 17 national public television shows about the brain and his online videos on brain and mental health have been viewed over 300 million times.

        Dr. Amen is a 12-time New York Times bestselling author, including Change Your Brain, Change Your Life, The End of Mental Illness, Healing ADD, and many more. His latest book, Change Your Brain Every Day: Simple Daily Practices to Strengthen Your Mind, Memory, Moods, Focus, Energy, Habits, and Relationships, is available now.

        WHY BRAINMD Empty heading

        Brain care is central to your success and well-being. Properly nourishing the organ that controls how your body functions can support your physical and functional health, as well as improve your mental outlook and clarity.

        Customer Reviews

        FAQs

        Is Happy Saffron Plus vegan-friendly?

        Yes — this formula is suitable for vegans and made without animal ingredients.

        Will it make me “hooked” or dependent?

        No — Happy Saffron Plus is a dietary supplement, not a drug, and is not habit-forming.

        Can I take Happy Saffron Plus with other mood products?

        Yes — it can be used together with other BrainMD mood-support supplements without needing to stop other products.

        What benefits might I experience?

        Users may experience support for mood enhancement, emotional balance, better focus, memory support, and overall well-being, thanks to the synergistic blend of saffron, curcumin, and zinc.